Detection of micrometastasis in bone marrow of pancreatic cancer patients
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چکیده
منابع مشابه
MUC2 mRNA detection in peripheral blood and bone marrow of breast cancer patients reveals micrometastasis
Tumor dissemination to distant organ is the cause of death. Therefore there is urgent set up sensitive methods for early dete circulating tumor cells (CTCs) and disse tumor cells (DTCs) in peripheral blood (P bone marrow (BM) specimens of breas patients. We aim to detect MUC2 mRNA cells in PB and BM of breast cancer pati relate this to patient relapse. In this stud tect MUC2 mRNA positive cells...
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Immunocytochemical detection of disseminated tumour cells in the bone marrow of patients with primary breast cancer at surgery has been shown to be an independent prognostic factor in single institutional studies and in a large pooled analysis. However, bone marrow sampling and assessment of disseminated tumour cells is not a routine procedure in the clinical management of patients with breast ...
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Present diagnostic techniques do not allow the detection of early metastatic spread of tumor cells, although this spread largely determines the clinical course of patients with small primary cancers. By use of monoclonal antibody CK2 to the epithelial cytokeratin component number 18 (CK18), individual disseminated carcinoma cells present in bone marrow of cancer patients can now be identified (...
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In a subset of patients with early gastric cancer, there were recurrences of the disease after a curative resection had been done. Direct evidence of tumor seeding in distant organs at the time of surgery for gastric cancer is not available. An immunocytochemical assay for epithelial cytokeratin protein may fill this gap because it is a feature of epithelial cells that would not normally be pre...
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Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1999
ISSN: 0923-7534
DOI: 10.1093/annonc/10.suppl_4.s111